Ofloxacin is an antibiotic useful for the treatment of a number of bacterial infections. When taken . Oral and intravenous ofloxacin are not licensed for use in children, except as noted above, due to the risk of musculoskeletal injury. In one study Pregnancy category: US: C (Risk not ruled out). Find patient medical information for Ofloxacin Intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Fluoroquinolones, including ofloxacin, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further.
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Tendinitis and tendon rupture, sometimes bilateral, may occur within 48 hours of starting treatment with ofloxacin and have been reported ofloxacin infusion to several months after discontinuation of.
The risk of tendinitis and tendon rupture is increased in patients aged over 60 years and in patients using corticosteroids. Ofloxacin infusion, as transplanted patients are at increased risk of tendinitis, caution is recommended when fluoroquinolones are used in this population.
The daily dose should be adjusted in elderly patients based on ofloxacin infusion clearance see section 4.
Close monitoring of these patients is therefore necessary if they are prescribed ofloxacin. All patients should consult their physician if they experience symptoms ofloxacin infusion tendinitis. If tendinitis is suspected, treatment with ofloxacin must be halted ofloxacin infusion, and appropriate treatment e.
Patients with renal impairment Since ofloxacin is ofloxacin infusion excreted by ofloxacin infusion kidneys, the dose of ofloxacin should be adjusted in patients with renal impairment see section 4.
QT interval prolongation Very rare cases of QT interval prolongation have been reported in patients taking fluoroquinolones.
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Caution should be taken when using fluoroquinolones, including ofloxacin, in patients with known risk factors for prolongation of the QT interval such as, for example: Therefore, caution should be taken when using fluoroquinolones, including Ofloxacin, in these populations.
Patients with history of psychotic disorder Psychotic reactions have been reported in patients receiving fluoroquinolones. In some cases these have progressed to suicidal thoughts or self-endangering behaviour including suicide attempt, sometimes after a single dose see section 4.
Ofloxacin infusion the event ofloxacin infusion a patient develops these reactions, ofloxacin should be discontinued and appropriate measures instituted.
Ofloxacin should be used with caution in patients with a history of psychotic disorder or in patients with psychiatric disease.
Ofloxacin 2 MG Infusion - Uses, Side Effects, Substitutes, Composition And More | Lybrate
ofloxacin infusion Elderly No adjustment of dosage is required in the elderly, other than that imposed by consideration of renal or hepatic function, Duration of Treatment The duration of treatment is determined according to the ofloxacin infusion of the causative organisms and the clinical picture.
As with all antibacterial agents, treatment with ofloxacin should be continued for at least 3 days after the body temperature has returned to normal and the symptoms have subsided. In most cases of acute infection, a course of treatment lasting days is sufficient. Once the patient's condition has improved, the mode of administration should be changed from parenteral ofloxacin infusion oral, normally at the same total daily dose.
Treatment should ofloxacin infusion exceed 2 months duration. Hypersensitivity to the active substance or to any of the excipients.
Ofloxacin should not be used in patients with a past history of tendinitis.
Tarivid IV Infusion Solution - Summary of Product Characteristics (SmPC) - (eMC)
Ofloxacin, like other 4-quinolones, ofloxacin infusion contraindicated in patients with a history of epilepsy or with a lowered seizure threshold. Ofloxacin is contraindicated in children or growing adolescents, and in pregnant or breastfeeding women, since animal experiments do not entirely exclude the risk of damage to the cartilage of joints in the growing subject.
Patients with latent or actual defects in glucosephosphate dehydrogenase activity may be prone to haemolytic reactions when treated with quinolone antibacterial agents.
Warnings and Precautions Ofloxacin ofloxacin infusion not the drug of first choice for pneumonia caused ofloxacin infusion Pneumococci or Mycoplasma, or angina tonsillar is caused by beta-haemolytic Streptococci.
Hypersensitivity and allergic reactions have been reported for fluoroquinolones ofloxacin infusion first administration. Anaphylactic and anaphylactoid reactions can progress to life-threatening shock, even after the first administration.